Multiple antibiotic resistance gene transfer from animal to human enterococci in the digestive tract of gnotobiotic mice.
نویسندگان
چکیده
It has been proposed that food animals represent the source of glycopeptide resistance genes present in enterococci from humans. We demonstrated the transfer of vanA and of other resistance genes from porcine to human Enterococcus faecium at high frequency in the digestive tract of gnotobiotic mice. Tylosin in the drinking water favored colonization by transconjugants.
منابع مشابه
انتقال ژنهای بیماریزایی و مقاومت آنتیبیوتیکی در گونههای انتروکوک از طریق کانجوگاسیون
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Background: Enterococci are part of normal flora of the human gastrointestinal tract, which have a high potential for acquiring antibiotic resistance genes. The widespread use of antibiotics in the agricultural and food industriel leads to release of resistance genes in pathogens and normal flora bacteria, transfer to human and also the cause of the disease, which is a serious menace to human h...
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 47 9 شماره
صفحات -
تاریخ انتشار 2003